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 | Food allergies and contact aeroallergens (such as pet dander and dust mites), are common triggers for atopic dermatitis. Irritants and dry weather can also worsen symptoms. People with atopic dermatitis may also have a flare in their symptoms due to an infection caused by bacteria, fungi or viruses. It can be difficult to predict when a flare of atopic dermatitis may occur, but once itching has become severe and scratching occurs, it can be difficult to get symptoms under control. There is a need for a biomarker for atopic dermatitis that can be followed to predict exacerbations of atopic dermatitis. Urinary biopyrrin may represent a biomarker for atopic dermatitis that could help predict exacerbations before they occur, so that appropriate treatments can be started in order to prevent severe attacks. |
| Urinary Biopyrrin is a Biomarker for Atopic Dermatitis Severity
Recently, a group of researchers from Japan discovered an association between urinary biopyrrin and atopic dermatitis severity. Biopyrrin, a metabolite of bilirubin, is excreted in the urine, and is a marker of inflammation in the body. Urinary biopyrrin has been previously shown to be elevated...
| Everything You Need to Know About Eczema
Eczema (also known as atopic dermatitis) is a chronic, recurrent skin disease that commonly occurs in early childhood but can continue or start in adulthood. Like other allergies and asthma, atopic dermatitis tends to run in families. Eczema typically begins as an itch that when scratched, erupts into a rash. The rash may occur anywhere on the body, although certain areas of the body are more common depending on the age of the person. Eczema initially appears as small red bumps, or vesicles, which can ooze or flake with continued scratching. As the skin continues to be scratched, it will appear leathery, or lichenified.
| Immunotherapy for Atopic Dermatitis
Various studies have been conducted in recent years to examine the possibility that allergy shots may actually be helpful for the treatment of atopic dermatitis. A number of these studies revealed that allergy shots are helpful in reducing the amount of atopic dermatitis symptoms (as measured by SCORAD -- a tool useful in assigning a numerical value based on the amount of skin involved, from 1 to 100) as well as reducing the amount of topical steroids required to control symptoms. Allergy shots were most effective at treating people with more severe atopic dermatitis, with SCORAD values greater than 40, as well as for people with dust mite allergies as a trigger for their atopic dermatitis.
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